Tadalafil, a phosphodiesterase type 5 inhibitor, is the active ingredient in
tadarise 40mg tablets, which are used to treat erectile dysfunction in men. During sexual stimulation, the erectile tissue of the penis releases nitric oxide, which activates the guanylate cyclase enzyme. An erection is brought on by this enzyme's elevation of the chemical cyclic guanosine monophosphate (cGMP), which relaxes the blood vessels in the penis and permits blood to fill the spongy erectile tissues.
An erection ends when another enzyme called phosphodiesterase type 5 (PDE5) breaks down cGMP and stops blood flow to the penis. Tadalafil, the active ingredient in
Tadarise, works to treat erectile dysfunction by facilitating the cGMP mechanism's natural activation during sexual stimulation.
